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國立臺東大學校長室
welcome NTTU office of president
曾耀銘校長簡歷

【現職】

  • 國立臺東大學校長 (2016/2~)
  • 國立臺東大學生命科學學系教授 (2016/8~)
  • 朝陽科技大學榮譽講座教授 (2016/2~)
     

【學歷】

  • 多倫多大學化學工程與應用化學學系博士 (1987/11)
  • 多倫多大學化學工程與應用化學學系碩士 (1983/6)
  • 國立清華大學工業化學學系學士 (1977/6)

 

【學術專長】

  • 生物技術-中草藥活性物質、真菌代謝物、生物性農藥、牛樟芝子實體培養
  • 生化工程-微生物發酵程序、分離純化技術、生化反應器、生物程序工程
  • 應用化學-天然物化學、藥物化學、結構鑑定、分析檢測
     

【學術經歷】

  • 國立臺東大學通識教育中心教授 (2016/2~2016/7)
  • 北京化工大學客座教授 (2015/4~2016/1)
  • 朝陽科技大學生物技術研究所教授 (2003/8~2016/1)
  • 朝陽科技大學應用化學系教授 (2000/8~2016/1)
  • 國立東華大學生命科學學系教授 (1997/8~2000/7)
  • 國立東華大學生物技術研究所教授 (1996/8~2000/7)
  • 大葉工學院食品工程學系教授 (1995/8~1996/7)
  • 大葉工學院食品工程學系副教授 (1990/8~1995/7)
  • 財團法人生物技術開發中心產程開發組副研究員 (1988/6~1990/7)
  • 中國文化大學生物科技研究所兼任副教授 (1989/8~1990/1、1990/8~1991/1)
  • 國立臺北工業專科學校化學工程科兼任副教授 (1988/9~1989/7、1989/9~1990/7)
  • 國立臺灣工業技術學院化學工程系兼任副教授 (1988/8~1990/7)
     

【行政經歷】

  • 朝陽科技大學副校長 (2003/8~2008/7)
  • 朝陽科技大學理工學院院長 (2000/8~2004/7)
  • 國立東華大學生命科學學系系主任 (1997/8~2000/7)
  • 國立東華大學生物技術研究所所長 (1996/8~2000/7)
  • 大葉工學院食品工程學系系主任 (1995/8~1996/7)
  • 大葉工學院食品工程學系代理系主任 (1990/8~1995/7)
  • 台灣省菸酒公賣局南投酒廠製酒技士兼製酒股股長 (1979/10~1983/12)
     

【專業學會及社會服務】

  • 台灣生物技術與生化工程學會(中華生化工程學會)理事 (2001/6~2019/6)
  • 亞洲生物技術聯盟(AFOB)副理事長 (2014/10~2018/9)
  • 中華工程教育學會會員委員會委員 (2003/11~2017/6)
  • 亞洲生物技術聯盟生物藥學與醫學生物技術學部召集人 (2014/10~2016/9)
  • 易宏生物科技股份有限公司(證劵代號:7421)董事 (2013/6~2016/1)
  • 中國國民黨廉能委員會委員 (2010/7~2016/1)
  • 財團法人波錠文教基金會董事 (2003/6~2015/5)
  • 亞洲生物技術聯盟理事 (2010/10~2014/9)
  • 台灣休閒航空協會理事長 (2006/8~2014/5)
  • 中華生化工程學會理事長 (2010/6~2013/6)
  • 財團法人臺灣省波錠社會福利公益慈善事業基金會董事 (2004/2~2013/5)
  • 中華民國科學展覽會設計指導委員會委員 (2005年、2006年)
     

【學術獎勵及榮譽事蹟】

  • 中華生化工程學會 生化工程獎章 (2015/6);生化工程獎章為中華生化工程學會頒發之最高學術榮譽,得獎人並正式獲邀請在當年度學會年會發表專題演講。
  • 科技部103年度「補助大專校院獎勵特殊優秀人才措施」審定獎勵。
  • 行政院國家科學委員會102年度、101年度、100年度、99年度「補助大專校院獎勵特殊優秀人才措施」審定獎勵。
  • 教育部102年度技專校院產學研發最新成果發表記者會(教育部陳德華政務次長主持)-優勝作品-用於抑制癌細胞生長之含安卓幸藥學組成物(已獲中華民國、中國大陸、美國等專利)。
  • 教育部100年度中區技職校院區域教學資源中心:研究類校際優良教師_朝陽科技大學生化科技研究所曾耀銘老師。
  • 行政院國家科學委員會98年度「技術移轉獎勵」,朝陽科技大學生化科技研究所曾耀銘教授「魚針草相關保健食品產品製備技術」技術移轉案。
  • 行政院國家科學委員會大學生研究創作獎指導教授獎狀3次(1994, 1995, 2000)。
  • YABEC Award, Young Asian Biochemical Engineers’ Community (2007)
  • Visiting Fellowships in Canadian Government Laboratories--Biotechnology Research Institute, National Research Council Canada (1989)
  • 1987 Canada Awards for Business Excellence - Invention Category, Bronze Trophy, Ministry of Regional Business Development and Industry, Canada
  • 1987 Outstanding Scientific Achievement Award, Eastern Canada Chinese Institute of Arts and Sciences
  • 1986 Youth Achievement Award, Chinese Community Centre of Ontario Canada
  • Junior Fellow of Massey College in the University of Toronto (1985, 1986, 1987)
     

【學術期刊論文發表】

  1. Lu KT, Wang BY, Chi WY, Ju CC, Yang JJ, Lee HT, Tzeng YM* and Chang WW*. 2016. Ovatodiolide Inhibits breast cancer stem/progenitor cells through SMURF2-mediated downregulation of Hsp27. Toxins, 8(1): 127-137.
  2. Chen CS, Wang ML, Huang Liu R, Chen SP, Lu TM, Tsai WY, Huang CF, Yang CC*, Tzeng YM*. 2016. Anti-fatigue effects of Anisomeles indica (L.) Kuntze aqueous extract in mice. Tropical Journal of Pharmaceutical Research, 15(3): 489-495.
  3. Hsieh YJ, Tseng SP, Kuo YH, Chiang CY, Tzeng YM*, Tsai WC*. 2016. Ovatodiolide of Anisomeles indica, exerts the anti-cancer potential on pancreatic cancer cell lines through STAT3 and NF-κB regulation. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 8680372, 10 pages.
  4. Chiu KY, Wu CC, Chia CH, Hsu SL* and Tzeng YM*. 2016. Inhibition of growth, migration and invasion of human bladder cancer cells by antrocin, a sesquiterpene lactone isolated from Antrodia cinnamomea, and its molecular mechanisms. Cancer Letters, 373(2): 174-184.
  5. Wang Q, Qiao X, Qian Y, Li ZW, Tzeng YM, Zhou DM, Guo DA, Ye M*. 2015. Intestinal Absorption of Ergostane and Lanostane Triterpenoids from Antrodia cinnamomea Using Caco-2 Cell Monolayer Model. Natural Products and Bioprospecting, 5(5): 237-246.
  6. Chang TC, Yeh CT, Adebayo BO, Lin YC, Deng L, Rao YK, Huang CC, Lee WH, Wu ATH, Hsiao M, Wu CH, Wang LS*, and Tzeng YM*. 2015. 4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype. Toxicology and Applied Pharmacology, 288(2): 258-268.
  7. Tzeng YM and Lee MJ*. 2015. Neuroprotective properties of kavalactones. Neural Regeneration Research, 10(6): 875-877.
  8. Qiao X, Song W, Wang Q, Liu KD, Zhang ZX, Bo T, Li RY, Liang LN, Tzeng YM*, De-an Guo DA, and Ye M*. 2015. Comprehensive chemical analysis of triterpenoids and polysaccharides in the medicinal mushroom Antrodia cinnamomea. RSC Advances, 5: 47040-47052.
  9. Qiao X, Wang Q, Ji S, Huang Y, Liu KD, Zhang ZX, Bo T, Tzeng YM, Guo DA, and Ye M*. 2015. Metabolites identification and multi-component pharmacokinetics of ergostane and lanostane triterpenoids in the anticancer mushroom Antrodia cinnamomea. Journal of Pharmaceutical and Biomedical Analysis, 111: 266-276.
  10. Kao MC, Rao YK, Hsieh YW, Weng SH, Lu TL, Tzeng DTW, Liu JJ, Lin CJ, Lai CH*, and Tzeng YM*. 2015. A cyclohexadepsipeptide from entomogenous fungi Metarhizium anisopliae inhibits the Helicobacter pylori induced pathogenesis through attenuation of vacuolating cytotoxin-A activity. Process Biochemistry, 50(1): 134-139.
  11. Liao YF*, Tzeng YM, Hung HC, and Liu GY. 2015. Dibenzoylmethane, hydroxydibenzoylmethane and hydroxymethyldibenzoylmethane inhibit phorbol-12-myristate 13-acetate induced breast carcinoma cell invasion. Molecular Medicine Reports, 11(2): 4597-4604.
  12. Rao YK, Cheng WT, Lee YC, Hung HC, Tzeng YM, and Lee MJ*. 2014. Purification of kavalactones from Alpinia zerumbet and their protective actions against hydrogen peroxide-induced apoptosis in PC12 cells. Journal of Bioscience and Bioengineering, 118(6): 679-688.
  13. Qiao X, An R, Huang Y, Ji S, Li L, Tzeng YM, Guo DA, and Ye M*, 2014, Separation of 25R/S-ergostane triterpenoids in the medicinal mushroom Antrodia camphorata using analytical supercritical- fluid chromatography. Journal of Chromatography A, 1358: 252-260.
  14. Huang LR, Chen SP, Lu TM, Tsai WY, Tsai CH, Yang CC*, and Tzeng YM*, 2014, Selective apoptotic cell death effects of oral cancer cells treated with destruxin B. BMC Complementary and Alternative Medicine, 14:207.
  15. Lai CK, Rao YK, Chang KR, Lin CW, Su HL, Chang CS, Lai CH*, Tzeng YM*, 2014, 3,3′,4′,5′-tetramethoxychalcone inhibits human oral cancer cell proliferation and migration via p53-mediated mitochondrial-dependent apoptosis. Anticancer Research, 34(4): 1811-1819.
  16. Huynh TT, Rao YK, Lee WH, Chen HA, Le TDQ, Tzeng DTW, Wang LS, Wu ATH, Lin YF, Tzeng YM*, Yeh CT*, 2014, Destruxin B inhibits hepatocellular carcinoma cell growth through modulation of the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition. Toxicology in vitro, 28(4): 552-561.
  17. Huang Y, Lin X, Qiao X, Ji S, Liu K, Yeh CT, Tzeng YM*, Guo D, and Ye M*, 2014, Antcamphins A-L, Ergostanoids from Antrodia camphorata. Journal of Natural Products, 77(1): 118-124.
  18. Yeh CT, Huang WC, Rao YK, Ye M, Lee WH, Wang LS, Tzeng DTW, Wu CH, Shieh YS, Huang CY, Chen YJ, Hsiao M, Wu ATH, Yang Z*, and Tzeng YM*, 2013, A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells. Carcinogenesis, 34(12): 2918-2928.
  19. Rao YK, Geethangili M, and Tzeng YM*, 2013, Development of a high performance liquid chromatography method for the quantitative determination of bioactive triterpenoids in the extracts of Antrodia camphorata. Analytical Methods, 5(20): 5724-5730.
  20. Wu CC, Chen TH, Liu BL, Wu LC, Chen YC, Tzeng YM* and Hsu SL*, 2013, Destruxin B isolated from entomopathogenic fungus Metarhizium anisopliae induces apoptosis via a Bcl-2 family-dependent mitochondrial pathway in human non-small cell lung cancer cells. Evidence-based Complementary and Alternative Medicine, Volume 2013, Article ID 548929, 11 pages.
  21. Rao YK, Chen YC, Fang SH, Lai CH, Geethangili M, Lee CC*, and Tzeng YM*, 2013, Ovatodiolide inhibits the maturation of allergen-induced bone marrow-derived dendritic cells and induction of Th2 cell differentiation. International Immunopharmacology, 17(9): 617-624.
  22. Geethangili M, Rao YK, and Tzeng YM*, 2013, Development and validation of a high-performance liquid chromatographic method for determination of antrocin, a dual Akt and mTOR inhibitor from Antrodia camphorata. International Journal of Applied Science and Engineering, 11(2): 195-201.
  23. Peng CY, Fong PC, Yu CC, Tsai WC, Tzeng YM, and Chang WW*, 2013, Methyl antcinate A suppresses the population of cancer stem-like cells in MCF7 human breast cancer cell line. Molecules, 18(3): 2539-2548.
  24. Lin CJ, Rao YK, Hung CL, Feng CL, Hsien, Lane HY, Tzeng DTW, Hsu PN, Lai CH*, and Tzeng YM*, 2013, Inhibition of Helicobacter pylori CagA-Induced Pathogenesis by Methylantcinate B from Antrodia camphorata. Evidence-based Complementary and Alternative Medicine, Volume 2013, Article ID 682418, 12 pages.
  25. Liu BL and Tzeng YM*, 2012, Development and applications of dextruxins: A review. Biotechnology Advances, 30(6): 1242-1254.
  26. Liao YF, Rao YK, and Tzeng YM*, 2012, Aqueous extract of Anisomeles indica and its purified compound exerts anti-metastatic activity through inhibition of NF-κB/AP-1-dependent MMP-9 activation in human breast cancer MCF-7 cells. Food and Chemical Toxicology, 50(8): 2930-2936.
  27. Lee YP, Wang CW, Liao WC, Yang CR, Yeh CT, Tsai CH, Yang CC* and Tzeng YM*, 2012, In vitro and in vivo anticancer effects of destruxin B on human colorectal cancer. Anticancer Research, 32(7): 2735-2745.
  28. Lee YP, Tsai WC, Ko CJ, RaoYK, Yang CR, Chen DR, Yang MH, Yang CC* and Tzeng YM*, 2012, Anticancer effects of eleven triterpenoids derived from Antrodia camphorata. Anticancer Research, 32(7): 2727-2734.
  29. Yeh CT, Rao YK, Ye M, Wu WS, Chang TC, Wang LS, Wu CH, Wu ATH*, and Tzeng YM*, 2012, Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging. Toxicology and Applied Pharmacology, 261(1): 31-41.
  30. Rao YK, Lien HM, Lin YH, Hsu YM, Yeh CT, Chen CC, Lai CH*, and Tzeng YM*, 2012, Antibacterial activities of Anisomeles indica constituents and their inhibition effect on Helicobacter pylori-induced inflammation in human gastric epithelial cells. Food Chemistry, 132(2): 780-787.
  31. Tzeng YM, Lee YC, Cheng WT, Wang HC, Shih HN, Rao YK, Lee MJ*, 2012, Effects of andrographolide and 14-deoxy-11,12-didehydroandrographolide on cultured primary astrocytes and PC12 cells. Life Sciences, 90(7-8): 257-266.
  32. Hsieh YC, Rao YK, Whang-Peng J, Huang CYF, Shyue SK, Hsu SL*, and Tzeng YM*, 2011, Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway. Journal of Agricultural and Food Chemistry, 59(20): 10943-10954.
  33. Rao YK, Wu ATH, Geethangili M, Huang MT, Chao WJ, Wu CH, Deng WP, Yeh CT*, and Tzeng YM*, 2011, Identification of Antrocin from Antrodia camphorata as Selective, and a Novel Class of Small Molecule Inhibitor of Akt/mTOR Signaling in Metastatic Breast Cancer MDA-MB-231 Cells. Chemical Research in Toxicology, 24(2): 238-245.
  34. Rao YK, Lee MJ, Chen K, Lee YC, Wu WS, and Tzeng YM*, 2011, Insulin-mimetic action of rhoifolin and cosmosiin isolated from Citrus grandis (L.) Osbeck leaves: enhanced adiponectin secretion and insulin receptor phosphorylation in 3T3-L1 cells. Evidence-based Complementary and Alternative Medicine, Volume 2011, Article ID 624375, 9 pages.
  35. Geethangili M and Tzeng YM*, 2011, Review of pharmacological effects of Antrodia camphorata and its bioactive compounds. Evidence-based Complementary and Alternative Medicine, Volume 2011, Article ID 212641, 17 pages.
  36. Lee MJ, Rao YK, Chen K, Lee YC, Chung YS, and Tzeng YM*, 2010, Andrographolide and 14-Deoxy-11,12-didehydroandrographolide attenuate high glucose-induced fibrosis and apoptosis in murine renal mesangeal cell lines. Journal of Ethnopharmacology, 132(2): 497-505.
  37. Rao YK, Kao TY, Ko JL*, Tzeng YM*, 2010, Chalcone HTMC causes in vitro selective cytotoxicity, cell cycle G1 phase arrest through p53-dependent pathway in human lung adenocarcinoma A549 cells, and in vivo tumor growth suppression. Bioorganic & Medicinal Chemistry Letters, 20(22): 6508-6512.
  38. Tsai WC, Rao YK, Lin SS, Chou MY, Shen YT, Wu CH, Geethangili M, Yang CC*, Tzeng YM*, 2010, Methylantcinate A induces tumor specific growth inhibition in oral cancer cells via Bax-mediated mitochondrial apoptotic pathway. Bioorganic & Medicinal Chemistry Letters, 20(20): 6145-6148.
  39. Rao YK, Kao TY, Wu MF, Ko JL*, Tzeng YM*, 2010, Identification of potent small molecule to inhibit telomerase activity through down regulation of hTERT and calcium induction pathway in human lung adenocarcinoma A549 cells. Bioorganic & Medicinal Chemistry, 18(19): 6987-6994.
  40. Rao YK, Fang SH, Wu WS, and Tzeng YM*, 2010, Constituents isolated from an edible mushroom Cordyceps militaris suppress enhanced inflammatory mediator’s production and human cancer cell proliferation. Journal of Ethnopharmacology, 131(2): 363-367.
  41. Lai CH, Rao YK, Fang SH, Shing YT, Tzeng YM*, 2010, Identification of 3',4',5'-trimethoxychalcone analogues as potent inhibitors of Helicobacter pylori-induced inflammation in human gastric epithelial cells. Bioorganic & Medicinal Chemistry Letters, 20(18): 5462-5465.
  42. Hsieh YC, Rao YK, Wu CC, Huang CY, Geethangili M, Hsu SL*, Tzeng YM*, 2010, Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and bax-triggered mitochondrial pathway. Chemical Research in Toxicology, 23(7): 1256-1267.
  43. Male KB, Crowley SM, Collins SG, Tzeng YM, Luong JHT*, 2010, Cell-based impedance spectroscopy for probing inhibitory effects of steroids and ergostane/lanosta-related compounds. Analytical Methods, 2(7): 870-877.
  44. Geethangili M, Fang SH, Lai CH, Rao YK, Lien HM, and Tzeng YM*, 2010, Inhibitory effect of Antrodia camphorata constituents on the Helicobacter pylori-associated gastric inflammation. Food Chemistry, 119(1): 149-153.
  45. Rao YK, Fang SH, and Tzeng YM*, 2009, Synthesis and biological evaluation of 3′,4′,5′-trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation. Bioorganic & Medicinal Chemistry, 17(23): 7909-7914.
  46. Lee MJ, Rao YK, Chen K, Lee YC and Tzeng YM*, 2009, Effect of flavonol glycosides from Cinnamomum osmophloeum leaves on adiponectin secretion and phosphorylation of insulin receptor-β in 3T3-L1 adipocytes. Journal of Ethnopharmacology, 126(1): 79-85.
  47. Rao YK, Geethangili M, Chan HS, Wu WS, and Tzeng YM*, 2009, High-performance liquid chromatographic dectermination of kaempferol glycosides in Cinnamomum osmophloeum leaves. International Journal of Applied Science and Engineering, 7(1): 1-9.
  48. Yeh CT, Rao YK, Yao CJ, Yeh CF, Li CH, Chuang SE, Luong JHT, Lai GM*, and Tzeng YM*, 2009, Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells. Cancer Letters, 285(1): 73-79.
  49. Majid E, Male KB, Tzeng YM*, Omamogho JO, Glennon JD, and Luong JHT*, 2009, Cyclodextrin modified capillary electrophoresis for achiral and chiral separation of ergostane and lanostane compounds extracted from the fruiting body of Antrodia camphorata. Electrophoresis, 30(11): 1967-1975.
  50. Male KB, Tzeng YM*, Montes J, Liu BL, Liao WC, Kamen A, and Luong JHT*, 2009, Probing inhibitory effects of destruxins from Metarhizium anisopliae using insect cell-based impedance spectroscopy: inhibition vs chemical structure. Analyst, 134(7): 1447-1452.
  51. Tzeng YM, Chen K, Rao YK, and Lee MJ*, 2009, Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes. European Journal of Pharmacology, 607(1-3): 27-34.
  52. Lu HH, Rao YK, Wu TZ, and Tzeng YM*, 2009, Direct characterization and quantification of volatile organic compounds by piezoelectric module chips sensor. Sensors & Actuators: B. Chemical, 137(2): 741-746.
  53. Rao YK, Fang SH, Shieh SC, Yeh TH, and Tzeng YM*, 2009, The constituents of Anisomeles indica and their anti-inflammatory activities. Journal of Ethnopharmacology, 121(2): 292-296.
  54. Rao YK, Lin HY, Wu WS, and Tzeng YM*, 2008, Quantitative analysis of lipopeptide antibiotic iturin A by high performance liquid chromatography and micellar electrokinetic chromatography. International Journal of Applied Science and Engineering, 6(2): 85-96.
  55. Male KB, Rao YK, Tzeng YM*, Montes J, Kamen A, and Luong JHT*, 2008, Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure. Chemical Research in Toxicology, 21(11): 2127-2133.
  56. Geethangili M, Rao YK, Fang SH, and Tzeng YM*, 2008, Cytotoxic constituents from Andrographis paniculata induce cell cycle arrest in Jurkat cells. Phytotherapy Research, 22(8): 1336-1341.
  57. Lai CH, Fang SH, Rao YK, Geethangili M, Tang CH, Lin YJ, Hung CH, Wang WC, and Tzeng YM*, 2008, Inhibition of Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells by Phyllanthus urinaria extracts. Journal of Ethnopharmacology, 118(3): 522-526.
  58. Rao YK, Fang SH, and Tzeng YM*, 2008, Anti-inflammatory activities of flavonoids and a triterpene caffeate isolated from Bauhinia variegata. Phytotherapy Research, 22(7): 957-962.
  59. Shieh SC, Fang SH, Rao YK, and Tzeng YM*, 2008, Inhibition of pro-inflammatory mediators and tumor cell proliferation by Anisomeles indica extracts. Journal of Ethnopharmacology, 118(1): 65-70.
  60. Tzeng YM*, Rao YK, Tsay KJ, and Wu WS, 2008, Effect of cultivation conditions on spore production from Bacillus amyloliquefaciens B128 and its antagonism to Botrytis elliptica. Journal of Applied Microbiology, 104(5): 1275-1282.
  61. Fang SH, Rao YK, and Tzeng YM*, 2008, Anti-oxidant and inflammatory mediator’s growth inhibitory effects of compounds isolated from Phyllanthus urinaria. Journal of Ethnopharmacology, 116(2): 333-340.
  62. Lin HY, Rao YK, Wu WS, and Tzeng YM*, 2007, Ferrous ion enhanced lipopeptide antibiotic Iturin A production from Bacillus amyloliquefaciens B128. International Journal of Applied Science and Engineering, 5(2): 123-132.
  63. Rao YK, Fang SH, and Tzeng YM*, 2007, Evaluation of the anti-inflammatory and anti-proliferation tumoral cells activities of Antrodia camphorata, Cordyceps sinensis, and Cinnamomum osmophloeum bark extracts. Journal of Ethnopharmacology, 114(1): 78-85.
  64. Liu BL, Rau TM, Rao YK, and Tzeng YM*, 2007, Effect of pH and aeration rate on enhanced production of destruxins A and B from Metarhizium anisopliae. International Journal of Applied Science and Engineering, 5(1): 17-26.
  65. Rao YK, Geethangili M, Fang SH, and Tzeng YM*, 2007, Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: a comparative study. Food and Chemical Toxicology, 45(9): 1770-1776.
  66. Rao YK, Tsay KJ, Wu WS, and Tzeng YM*, 2007, Medium optimization of carbon and nitrogen sources for the production of spores from Bacillus amyloliquefaciens B128 using response surface methodology. Process Biochemistry, 42(4): 535-541.
  67. Rao YK, Tsou JH, and Tzeng YM*, 2006, Antioxidants enhanced production of destruxin E from cultivation of Metarhizium anisopliae. Applied Microbiology and Biotechnology, 73(3): 519-524.
  68. Fang SH, Padmavathi V, Rao YK, Subbaiah DRCV, Thriveni P, Geethangili M, Padmajab A, and Tzeng YM*, 2006, Biological evaluation of sulfone derivatives as anti-inflammatory and tumor cells growth inhibitory agents. International Immunopharmacology, 6(11): 1699-1705.
  69. Maheswara M, Siddaiah V, Rao YK, Tzeng YM, and Sridhar C*, 2006, A simple and efficient one-pot synthesis of 1,4-dihydropyridines using heterogeneous catalyst under solvent-free conditions. Journal of Molecular Catalysis A - Chemical., 260: 179-180.
  70. 陳韋如、李國欽、高穗生*、曾耀銘、曾經洲,2006,台灣蘇力菌cry1Ac5殺蟲基因選殖及表現。植物保護學會會刊Plant Protection Bulletin),48(1):17-30.
  71. Rao YK, Chou CH, and Tzeng YM*, 2006, A simple and rapid method for identification and determination of cordycepin in Cordyceps militaris by capillary electrophoresis. Analytica Chimica Acta, 566(2): 253-258.
  72. Rao YK, Lu SC, Liu, BL, and Tzeng YM*, 2006, Enhanced production of an extracellular protease from Beauveria bassiana by optimization of cultivation processes. Biochemical Engineering Journal, 28(1): 57-66.
  73. Rao YK, Fang SH, and Tzeng YM*, 2006, Anti-inflammatory activities of constituents from Phyllanthus polyphyllus. Journal of Ethnopharmacology, 103(1): 181-186.
  74. Das B*, Mahender G, Rao YK, Ramesh C, Venkateswarlu K, Ravikumar K, Geethangili M, and Tzeng YM, 2006, Pseudoguaianolides from the flowers of Parthenium hysterophorus. Helvetica Chimica Acta, 89: 285-290.
  75. Rao YK, Fang SH, and Tzeng YM*, 2005, Synthesis, growth inhibition, and cell cycle evaluations of novel flavonoid derivatives. Bioorganic & Medicinal Chemistry, 13(24): 6850-6855.
  76. Rao YK, Fang SH, and Tzeng YM*, 2005, Anti-inflammatory activities of flavonoids isolated from Caesalpinia pulcherrima. Journal of Ethnopharmacology, 100(3): 249-253.
  77. Das R, Geethangili M, Majhi A, Das B*, Rao YK, and Tzeng YM, 2005, A new highly oxygenated pseudoguaianolide from a collection of the flowers of Parthenium hysterophorus. Chemical & Pharmaceutical Bulletin, 53(7): 861-862.
  78. Rao YK, Fang SH, and Tzeng YM*, 2005, Inhibitory effects of flavonoids isolated from Waltheria indica on the production of NO, TNF-α and IL-12 in activated macrophages. Biological & Pharmaceutical Bulletin, 28(5): 912-915.
  79. Fang SH, Rao YK, and Tzeng YM*, 2005, Inhibitory effects of flavonol glycosides from Cinnamomum osmophloeum on inflammatory mediators in LPS/IFN-r-activated murine macrophages. Bioorganic & Medicinal Chemistry, 13(7): 2381-2388.
  80. Peng KC*, Huang HS, Liu SY, and Tzeng YM, 2005, Circular dichroism analysis of destruxins from Metarhizium anisopliae. Journal of Biochemical and Biophysical Methods, 62(1): 41-50.
  81. Rao YK, Vimalamma G, Rao CV, and Tzeng YM*, 2004, Flavonoids and andrographolides from Andrographis paniculata. Phytochemistry, 65(16): 2317-2321.
  82. Fang SH, Rao YK, and Tzeng YM*, 2004, Cytotoxic effect of trans-Cinnamaldehyde from Cinnamomum osmophloeum leaves on human cancer cell lines, International Journal of Applied Science and Engineering, 2(2): 136-147.
  83. Rao YK, Fang SH, and Tzeng YM*, 2004, Differential effects of synthesized 2’ – oxygenated chalcone derivatives: modulation of human cell cycle phase distribution. Bioorganic & Medicinal Chemistry, 12(10): 2679-2686.
  84. Liu CM*, Huang SS, and Tzeng YM, 2004, Purification and quantitative analysis of destruxins from Metarhizium anisopliae by high-performance liquid chromatography. Journal of Liquid Chromatography and Related Technologies, 27(6): 1013-1025.
  85. Liu CM, Huang SS, and Tzeng YM*, 2004, Analysis of destruxins from Metarhizium anisopliae by capillary electrophoresis. Journal of Chromatographic Science, 42(3): 140-144.
  86. Feng KC, Rou TM, Liu BL, and Tzeng YM*, 2004, Effect of fungal pellet size on the high yield production of destruxin B by Metarhizium anisopliae. Enzyme and Microbial Technology, 34(1): 22-25.
  87. Liu BL, Kao PM, TzengYM*, and KC Feng, 2003, Production of Chitinase from Verticillium lecanii F091 using submerged fermentation. Enzyme and Microbial Technology, 33(6): 410-415.
  88. Feng KC, Liu BL, TzengYM*, 2003, Application of bioprocess engineering on microbial biopesticides. Plant Protection Bulletin, Spec. Publ. New 5: 195-219.
  89. Tsai SF, Liu BL, Liao JW, Wang JS, Hwang JS, Wang SC, Tzeng YM, and Ho SP*, 2003, Pulmonary toxicity of thuringiensin administered intratracheally in Sprague-Dawley rats. Toxicology, 186(3): 205-216.
  90. Chang YN*, Lin YC, Lee CC, Liu BL, and Tzeng YM, 2002, Effect of Rice-Glycerol complex Medium on the Production of Lovastatin by Monascus rubber. Folia Microbiologica, 47(6): 677-684.
  91. Liu CM, Tung CS, and Tzeng YM*, 2002, Quantitative analysis of biological and chemical insecticide mixture by capillary electrophoresis. Journal of Liquid Chromatography and Related Technologies, 25(20): 3213-3225.
  92. Chang YN, Huang JC, Lee CC, Shih IL*, and Tzeng YM, 2002, Use of response surface methodology to optimize culture medium for production of lovastatin by Monascus ruber. Enzyme and Microbial Technology, 30(7): 889-894.
  93. Feng KC, Liu BL, and Tzeng YM*, 2002, Morphological characterization and germination of aerial and submerged spores of an entomopathogenic fungus Verticillium lecanii. World Journal of Microbiology and Biotechnology, 18(3): 217-224.
  94. Liu CM, Liu BL, Tzeng YM*, and Tung CS, 2001, Purification of thuringiensin from Bacillus thuringiensis using calcium silicate adsorption and dibasic sodium phosphate desorption methods. Journal of the Chinese (Taiwan) Institute of Chemical Engineers, 32(6): 537-545.
  95. 曾耀銘*、饒梓明,2001,環狀脂胜肽黑殭菌素之生產與應用。生物資源 生物技術 (Bioresource Biotechnology),3(3): 42-46.
  96. Liu CM and Tzeng YM*, 2001, Quantitative analysis of parasporal crystal protein from Bacillus thuringiensis by capillary electrophoresis. Journal of Food and Drug Analysis, 9(2): 79-83.
  97. Feng KC, Liu BL, and Tzeng YM*, 2001, Morphology of parasporal endotoxin crystals from cultivations of Bacillus thuringiensis subsp. kurataki isolate A3-4. World Journal of Microbiology and Biotechnology, 17(2): 119-123.
  98. Liu BL, Chen JW, and Tzeng YM*, 2000, Production of cyclodepsipeptides destruxin A and B from Metarhizium anisopliae. Biotechnology Progress, 16(6): 993-999.
  99. Oh YS, Shih IL, Tzeng YM, and Wang SL*, 2000, Protease produced by Pseudomonas aeruginosa k-187 and its application in the deproteinization of shrimp and crab shell wastes. Enzyme and Microbial Technology, 27(1, 2): 3-10.
  100. Feng KC, Liu BL, and Tzeng YM*, 2000, Verticillium lecanii spore production in solid-state and liquid-state fermentations. Bioprocess Engineering, 23(1): 25-29.
  101. 劉炳嵐、馮國慶、曾耀銘*,2000,生物程序工程在生物性農藥產程的應用。化工 (Chemical Engineering - The Chin I. Ch. E.),47(2): 40-57.
  102. 曾耀銘*、吳文騰、高穗生、王順成,2000,生物農藥-蘇力菌素的研究開發。國科會科學發展月刊 (National Science Council Monthly),28(5): 350-353.
  103. Liu BL, Tzeng YM*, and Wei JD, 2000, Recovery of insecticidal activity of solubilized delta-endotoxin protein from Bacillus thuringiensis subsp. kurstaki. Pest Management Science, 56(5): 448-454.
  104. Yang, JK, Shih IL, Tzeng YM, and Wang SL*, 2000, Production and purification of protease from a Bacillus subtilis that can deproteinize crustacean wastes. Enzyme and Microbial Technology, 26(5,6): 406-413.
  105. Liu BL and Tzeng YM*, 2000, Characterization study on the sporulation kinetics of Bacillus thuringiensis. Biotechnology and Bioengineering, 68(1): 11-17.
  106. Liu BL, Jong CH, and Tzeng YM*, 1999, Effect of immobilization on pH and thermal stability of Aspergillus ficuum phytase. Enzyme and Microbial Technology. 25(6): 517-521.
  107. Tsun HY, Liu CM, and Tzeng YM*, 1999, Recovery and purification of thuringiensin from fermentation broth of Bacillus thuringiensis. Bioseparation, 7(6): 309-317.
  108. Feng KC, Jan XC. Liu BL, and Tzeng YM*, 1999, Microscopic studies of endospore and parasporal crystal in Bacillus thuringiensis subsp. kurstaki A3-4 from fermentor. Microscopy and Microanalysis, 5(S2): 1128-1129.
  109. Liu BL and Tzeng YM*, 1999, Water content and water activity for the production of cyclodepsipeptides in solid-state fermentation by Metarhizium anisopliae. Biotechnology Letters, 21(8): 657-661.
  110. Tzeng YM*, Tsun HY, and Chang YN, 1999, Recovery of thuringiensin with cetylpyridinium chloride using micellar-enhanced ultrafiltration process. Biotechnology Progress, 15(3): 580-586. (IF= 2.340; 25/128 Food Science & Technology)
  111. Chen JW, Liu BL, and Tzeng YM*, 1999, Purification and quantification of destruxins A and B from Metarhizium anisopliae. Journal of Chromatography A, 830(1): 115-125.
  112. 謝建元*、段淑人、王順成、高穗生、曾耀銘,1998,本土黑殭菌對甜菜夜蛾幼蟲之毒效探討。中國農業化學會誌 (Journal of the Chinese Agricultural Chemical Society), 36(6): 622-629.
  113. 謝建元*、洪文凱、高穗生、王順成、曾耀銘,1998,本土黑殭菌以固態和液態發酵生產黑殭菌素之探討。中國農業化學會誌 (Journal of the Chinese Agricultural Chemical Society), 36(4): 371-379.
  114. Liu CM and Tzeng YM*, 1998, Quantitative analysis of thuringiensin by high-performance liquid chromatography using adenosine monophosphate as an internal standard. Journal of Chromatographic Science, 36(7): 340-344.
  115. Liu BL and Tzeng YM*, 1998, Optimization of growth medium for the production of spores from Bacillus thuringiensis using response surface methodology. Bioprocess Engineering, 18(6): 413-418.
  116. Liu CM and Tzeng YM*, 1998, Quantitative analysis of thuringiensin by micellar electrokinetic capillary chromatography. Journal of Chromatography A, 809(1-2): 258-263.
  117. Liu BL, Rafiq A, Tzeng YM*, and Rob A, 1998, The induction and characterization of phytase and beyond - a review. Enzyme and Microbial Technology, 22(5): 415-424.
  118. Liu CM and Tzeng YM*, 1998, Application of capillary electrophoresis on pharmaceutical drug analysis. Journal of Food and Drug Analysis, 6(1): 391-403.
  119. 陳齊聖*、曾耀銘,1998,另類大豆-油菜籽。化工技術,6(2): 124-134.
  120. Hsu TH*, Tzeng YM, and Wu MM, 1997, Insecticidal activity and HPLC correlation of thuringiensin from fermentation and two-phase aqueous separation processes. Pesticide Science, 50(1): 35-41.
  121. Tzeng YM* and Young YH, 1996, Production of thuringiensin from Bacillus thuringiensis using a net-draft-tube modified airlift reactor. World Journal of Microbiology and Biotechnology, 12(1): 32-37.
  122. Jong JZ, Hsiun DY, Wu WT*, and Tzeng YM, 1995, Fed-batch culture of Bacillus thruingiensis for thuringiensin production in a tower type bioreactor. Biotechnology and Bioengineering, 48(3): 207-213.
  123. 曾耀銘*、鄭宏盈,1995,微胞強化超過濾技術回收蘇力菌素的測試與探討。技術學刊 (Journal of Technology), 10(2): 261-268.
  124. 曾耀銘*、邱琪雯,1995,醇-鹼溶液系統在油菜籽之硫代葡糖之萃取應用。食品科學 (Food Science), 22(4): 375-386.
  125. Tzeng YM* and Young YH, 1995, Penicillin-G enhanced production of thuringiensin by Bacillus thuringiensis subsp. darmstadiensis. Biotechnology Progress, 11(2): 231-234.
  126. 楊喻翔、曾耀銘*、徐泰浩,1994,蘇力菌素在攪拌槽、氣泡塔及網狀內管氣舉式醱酵槽製備之比較。大葉學報 (Journal of Da-Yeh Institute of Technology), 3(1): 55-69.
  127. 徐泰浩*、曾耀銘,1994,生物界面活性劑生產技術之開發與應用。化工 (Chemical Engineering - The Chin I. Ch. E.), 41(6): 42-56.
  128. 徐泰浩*、曾耀銘,1994,生物界面活性劑醱酵生產與分離純化,生物產業 (Bioindustry - Bioindustry Development Association), 5(1,2): 55-65.
  129. Jong JZ, Wu WT*, and Tzeng YM, 1994, pH control for fed-batch culture of Bacillus thuringiensis. Biotechnology Techniques, 8(7): 483-486.
  130. 曾耀銘*、吳美貌、徐泰浩,1993,兩水相萃取技術在生物殺蟲劑蘇力菌素的分離純化應用。大葉學報 (Journal of Da-Yeh Institute of Technology), 2(1): 109-122.
  131. 吳美貌、曾耀銘*、徐泰浩,1993,蘇力菌素高產率醱酵暨高效液相層析全程偵測探討。技術學刊 (Journal of Technology), 8(2): 223-230.
  132. 徐泰浩*、曾耀銘,張慈蘭,1992,蜂王乳葵稀酸成份高效液相層析分析與標準化。大葉學報 (Journal of Da-Yeh Institute of Technology), 1(1): 81-91.
  133. 徐泰浩*、曾耀銘,1992,利用醱酵技術開發機能性食物-冬蟲夏草。(Cordyceps)。國科會科學發展月刊 (National Science Council Monthly), 20(4): 388-397.
  134. 方銘崇、曾耀銘*、徐泰浩,1992,頭孢子菌素類抗生素雪華若林酸鹽轉化與醇水系統之溶解度研究。大葉學報 (Journal of Da-Yeh Institute of Technology), 1(1): 57-66.
  135. 徐泰浩*、曾耀銘,1992,生物技術在食品工業的應用。大葉學報 (Journal of Da-Yeh Institute of Technology), 1(1): 1-17.
  136. 徐泰浩*、曾耀銘,1991,利用微生物生產的生化殺蟲劑-亞弗麥丁素 (Avermectin)。國科會科學發展月刊 (National Science Council Monthly), 19(10): 1315-1326.
  137. Deng QY, Barefoot RR, Diosady LL*, Rubin LJ, and Tzeng YM, 1990, Lysinoalanine concentrations in rapeseed protein meals and isolates. Food Research International (Canadian Institute of Food Science and Technology Journal), 23(2/3): 140-142.
  138. Tzeng YM, Diosady LL*, Chen BK, and Rubin LJ, 1990, Ultrafiltration rejection coefficients of canola meal components. Food Research International (Canadian Institute of Food Science and Technology Journal), 23(2/3): 131-136.
  139. Tzeng YM, Diosady LL* and Rubin LJ, 1990, Production of canola protein materials by alkaline extraction, precipitation, and membrane processing. Journal of Food Science, 55(4): 1147-1151 & 1156.
  140. 劉炳嵐、曾耀銘*,1989,醱酵法生產的微生物殺蟲劑-Bacillus thuringiensis. 國科會科學發展月刊 (National Science Council Monthly), 17(12): 1460-1473.
  141. Tzeng YM, Diosady LL*, and Rubin LJ, 1988, Preparation of rapeseed protein isolate by sodium hexametaphosphate extraction, ultrafiltration, diafiltration, and ion-exchange. Journal of Food Science, 53(5): 1537-1541.
  142. Tzeng YM, Diosady LL*, and Rubin LJ, 1988, Preparation of rapeseed protein isolates using ultrafiltration, precipitation, and diafiltration. Food Research International (Canadian Institute of Food Science and Technology Journal), 21(4): 419-424.
  143. Diosady LL*, Tzeng YM, and Rubin LJ, 1984, Preparation of rapeseed protein concentrates and isolates using ultrafiltration. Journal of Food Science, 49(3): 768-770 & 776.
  144. Tzeng YM and Wu WT*, 1978, Viodage distribution in conical fixed bed. Journal of the Chinese (Taiwan) Institute of Chemical Engineers, 12(2): 161-163.


【研究成果技術移轉績效】

  • 油菜籽蛋白質工業製程技術-已由加拿大多倫多大學創新基金會授權Food Biotek Corporation, Canada進行商業化。本專利技術可望使人類運用油菜籽就如同運用黃豆一般的便利;如此,油菜籽將成為人類重要的食用油與食用蛋白質的來源。【註:全球油菜籽的年產量約為黃豆的三分之ㄧ強,油菜籽萃完油之粕含高量蛋白質,一般僅供飼料用途;本專利技術將導致大宗食用植物性蛋白質之新供給,對於全球之節能減碳將有深切影響】
     
  • 蘇力菌素相關環保及農業資材產品製備技術-由南帝化學工業股份有限公司暨行政院國科會支持執行產學合作研究計畫;整體技術已於民國95年6月12日由國科會授權旗艦銀河生物科技股份有限公司進行產業化(行政院國家科學委員會95年10月19日臺會綜三字第0950045099號函之技術移轉合約:NSC-P-095-00028)。【註:續歷經五年餘之持續輔導,旗艦銀河(琦豐)生物科技股份有限公司製造的「蘇力菌發酵液」終於在民國100年9月5日獲環保署審核通過,准予製造並核發該產品之「環境用藥許可證﹙環署微製第0006號﹚」,該公司並成為我國第一家以本土菌株與國內技術,生產防治蚊幼蟲「環境用藥微生物製劑」的公司;同時,該產品可望在國內外防治蚊幼蟲、登革熱、瘧疾等扮演相當角色。琦豐生技公司已進駐中部科學園區生產製劑應市】
     
  • 魚針草相關保健食品產品製備技術-由行政院國科會支持執行專題研究計畫;胃部調理保健食品組合物(抑制幽門螺旋菌) KNOW-HOW已於民國97年10月1日由朝陽科技大學授權優生生物科技股份有限公司進行產業化(行政院國家科學委員會98年3月11日臺會綜三字第0980013902號函之技術移轉合約:NSC-N-098-00009)。本技術移轉案獲得行政院國科會98年度「技術移轉獎勵」(行政院國家科學委員會98年9月10日臺會綜三字第0980066452號函)。
     
  • 牛樟椴木培養富含具抑制系列癌細胞或抑制幽門螺旋菌等功效天然化合物三萜類等之樟芝子實體的技術-由朝陽科技大學支持執行專題研究計畫;整體牛樟芝子實體培育技術已於民國101年7月31日由朝陽科技大學授權易宏生物科技股份有限公司進行產業化,該公司並以易宏生物科技股份有限公司普通股60萬股(600,000)股權(每股面額新台幣10元,股票面額總值新台幣6,000,000元)作為本技術移轉授權合約之權利金。易宏生技公司已於民國104年9月30日以每股新台幣35元登錄興櫃(證劵代號:7421)。
     
  • 黑殭菌相關植物保護產品製備技術-已於民國104年3月20日由朝陽科技大學非專屬授權陽田生物科技有限公司進行產業化。

 

【學術期刊編審】

  • International Journal of Applied Science and Engineering
    Editor-in-chief (2002~2004)
    Member of Editorial Board (2002 to date)
  • Botanics: Targets and Therapy
    Member of Editorial Board (2010 to date)
  • Biotechnology and Applied Biochemistry
    Member of Editorial Board and Associate Editor (2012 to date)
  • Evidence-based Complementary and Alternative Medicine
    Member of Editorial Board (2010 to date)
  • Journal of Bioscience and Bioengineering
    Member of Editorial Board and Handling Editor (2013 to date)